Drug intelligence / Profile preview

Dextran 10

Development stage
Preclinical
Lead developer
Pharmacosmos
Administration
Oral, Intravenous
01

Overview

Dextran 10 is a highly purified, non-toxic, branched glucose polymer (polysaccharide) with an average molecular weight of approximately 10,000 Daltons (10 kDa). It is produced via fermentation of Leuconostoc bacteria and consists predominantly of α-1,6 glycosidic linkages with some α-1,3 branches, making it highly water-soluble and biocompatible. While dextrans are broadly used in various medical applications, including as plasma volume expanders and antithrombotic agents, the provided clinical trial context specifically highlights its investigation as a dietary supplement for its effect on post-prandial glucose response. It is also available as an active pharmaceutical ingredient (API) or excipient for use in drug products and medical devices.

Brand names
Pharmacosmos Dextran 10Dextran 10 UltraDextran10 UltraDextran-10 Ultra
Other names
Dextran T10 MW 10,000Dextran T10 MW 8000-12000
02

Targets

PLG (Plasminogen)BB-031 (Von Willebrand factor)

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