dextromethorphan + chlorpheniramine maleate + guaifenesin

**Dextromethorphan + chlorpheniramine maleate + guaifenesin** is a fixed-dose, multi-ingredient over-the-counter (OTC) medication used primarily for temporary relief of symptoms associated with the common cold, including cough, congestion, runny nose, sneezing, itchy nose, and itchy or watery eyes[1][5]. The mechanism of action is multifactorial: - **Dextromethorphan** is a centrally acting cough suppressant that reduces the urge to cough by acting on the brain’s cough center[1][5]. - **Chlorpheniramine maleate** is a first-generation antihistamine that blocks histamine receptors, thus alleviating allergy symptoms such as runny nose, sneezing, itchy nose, and watery eyes[1][5]. - **Guaifenesin** is an expectorant that increases hydration of respiratory tract secretions, thinning mucus and making it easier to clear from the airways[1][5]. This combination is intended for both adults and children, though age restrictions and dosing should follow product labeling and medical advice. Common side effects include drowsiness, dizziness, dry mouth, nausea, and headache[5].

Brand names

Kids Cough Daytime Nighttime Combo