dextromethorphan + phenylpropanolamine + pheniramine

Dextromethorphan + phenylpropanolamine + pheniramine is a fixed-dose combination pharmaceutical product manufactured by Chemidrug Industries in Nepal. It is indicated for the symptomatic relief of cough and cold symptoms. The combination consists of three active ingredients: dextromethorphan, a centrally acting antitussive that suppresses the cough reflex by elevating the cough threshold; phenylpropanolamine, a sympathomimetic decongestant that reduces nasal congestion by constricting blood vessels in the nasal passages; and pheniramine, a first-generation antihistamine that alleviates allergic symptoms such as sneezing and rhinorrhea. This product is marketed as a generic cough preparation in the Nepalese market, where these active ingredients remain approved for clinical use despite phenylpropanolamine being withdrawn in several other global jurisdictions due to safety concerns.

Other names

Dextromethorphan, Phenylpropanolamine, Pheniramine