dextrose + local anesthetic

A combination of dextrose and a local anesthetic (such as lidocaine or bupivacaine) is used in various clinical settings, most commonly for regional anesthesia (including spinal, epidural, and peripheral nerve blocks), pain management procedures, and regenerative injection therapies like prolotherapy. The local anesthetic component acts by stabilizing neuronal membranes and inhibiting the ionic fluxes required for the initiation and conduction of nerve impulses, resulting in loss of sensation or pain relief. Dextrose serves primarily as a vehicle to adjust solution baricity (density relative to cerebrospinal fluid) for spinal/epidural use—making the solution hyperbaric—or as an active agent in regenerative therapies where it may promote tissue repair or modulate pain pathways. This combination is not a single branded product but rather a formulation used clinically with different local anesthetics depending on indication[1][3][5][7].