Drug intelligence / Profile preview

dextrose 5% in 0.45% sodium chloride

Development stage
Phase 4
Lead developer
Ives Drugs India
Modality
Small Molecules
Administration
Intravenous, Parenteral
01

Overview

Dextrose 5% in 0.45% Sodium Chloride is a sterile, nonpyrogenic, hypertonic intravenous solution used for fluid and electrolyte replenishment and caloric supplementation. Each 100 mL contains 5 grams of dextrose monohydrate and 0.45 grams of sodium chloride, providing 77 mEq/L of sodium and chloride ions along with 170 kcal/L. Sodium is the principal cation of the extracellular fluid and is essential for maintaining water distribution and osmotic pressure, while dextrose serves as a readily available energy source. This solution is indicated for patients requiring parenteral hydration and caloric intake, particularly when there is a need for both water and electrolytes. It is marketed generically by various manufacturers, including Ives Drugs India.

Brand names
5% Dextrose and 0.45% Sodium Chloride Injection
Other names
D5 1/2 NSD5 0.45% NaCl5% Dextrose and 0.45% Sodium Chloride Injection, USPD5 0.45 NSD-5 0.45 NSD 5 0.45 NS
02

Targets

ClC (CLC chloride channel family)

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