Drug intelligence / Profile preview

dextrose monohydrate + sodium lactate + calcium chloride + potassium chloride + sodium chloride

Development stage
Approved
Lead developer
Baxter Healthcare Corporation
Modality
Small Molecules
Administration
Intravenous, Parenteral
01

Overview

dextrose monohydrate + sodium lactate + calcium chloride + potassium chloride + sodium chloride is a sterile intravenous crystalloid and carbohydrate solution corresponding to **Lactated Ringer's and 5% Dextrose Injection**. It is used as a parenteral source of water, electrolytes, and calories, and as an alkalinizing agent. Pharmacologically, it does not act through a single receptor target; instead, it expands and replenishes the extracellular fluid compartment, supplies dextrose as a readily metabolized carbohydrate source, replaces key electrolytes including sodium, potassium, calcium, and chloride, and provides lactate that is metabolized to bicarbonate to help buffer metabolic acidosis. The product is used for replacement of extracellular fluid and electrolyte losses and for maintenance therapy in adults and pediatric patients who require intravenous fluid, electrolyte, and limited caloric support. Publicly described manufacturers include Hospira and ICU Medical.

Brand names
Lactated Ringer's and 5% Dextrose InjectionLactated Ringer's and Dextrose Injection
Other names
dextrose monohydrate + sodium lactate + calcium chloride + potassium chloride + sodium chlorideLactated Ringer's and 5% Dextrose Injection USPLactated Ringer's and Dextrose 5% InjectionD5LRD-5LRD 5LR

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