Drug intelligence / Profile preview

dextrose monohydrate + sodium lactate + potassium chloride + calcium chloride + sodium chloride

Development stage
Approved
Lead developer
ICU Medical
Modality
Small Molecules
Administration
Intravenous, Parenteral
01

Overview

This product is a **sterile intravenous crystalloid and carbohydrate combination solution** containing dextrose monohydrate, sodium lactate, potassium chloride, calcium chloride, and sodium chloride. It is used parenterally as a source of water, electrolytes, and calories, and as an alkalinizing agent. The pharmacologic effect is not mediated by a single receptor target; rather, the formulation restores extracellular fluid volume, replenishes sodium, potassium, calcium, and chloride losses, provides glucose calories through dextrose, and supplies lactate that is metabolized to bicarbonate, helping buffer metabolic acidosis. It is marketed as Lactated Ringer's and 5% Dextrose Injection and related potassium-containing Lactated Ringer's/dextrose presentations, and the provided context identifies ICU Medical as the manufacturer/distributor. The relevant clinical use is fluid and electrolyte replacement in adults and pediatric patients who require intravenous hydration, electrolyte repletion, minimal carbohydrate calories, and alkalinization.

Brand names
Lactated Ringer's and 5% Dextrose InjectionPotassium Chloride in Lactated Ringer's and Dextrose
Other names
dextrose monohydrate + sodium lactate + potassium chloride + calcium chloride + sodium chlorideLactated Ringer's and Dextrose InjectionPotassium Chloride in Lactated Ringer's and Dextrose InjectionPotassium Chloride in Lactated Ringer's and Dextrose 5% Injection

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