diacerein + glucosamine + methylsulfonylmethane

Cushion-OD is a fixed-dose combination pharmaceutical product developed by Tigris Lifesciences, specifically formulated for the orthopedic management of osteoarthritis and degenerative joint diseases. The medication combines three active ingredients: glucosamine sulfate, diacerein, and methylsulfonylmethane (MSM). Glucosamine serves as a fundamental building block for the synthesis of glycosaminoglycans and proteoglycans in the cartilage matrix and synovial fluid. Diacerein is an anthraquinone derivative that acts as a slow-acting drug in osteoarthritis (SYSADOA); it works by inhibiting the production and activity of interleukin-1 beta (IL-1β), a key cytokine responsible for cartilage degradation and joint inflammation. Methylsulfonylmethane (MSM) provides a source of organic sulfur, which is essential for maintaining the structural integrity of connective tissues and exerts mild anti-inflammatory and analgesic effects. Together, these components work synergistically to reduce joint pain, improve functional mobility, and potentially slow the progression of joint space narrowing.

Brand names

Cushion-OD

Other names

Cushion OD