Drug intelligence / Profile preview

Diakine Drug Conjugate

Development stage
Preclinical
Lead developer
DEKA Biosciences
Modality
Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes, Peptide-Drug Conjugates → Peptide Conjugates → Peptides
Administration
Intravenous
01

Overview

Diakine Drug Conjugate is a preclinical-stage tumor-directed drug conjugate developed by DEKA Biosciences. It is designed to deliver a cytotoxic payload specifically to cancer cells that are dependent on growth factors for survival and proliferation. The therapeutic utilizes DEKA's proprietary Diakine platform, which involves the engineering of cytokine fusion proteins, to target a wide array of malignancies. These include solid tumors such as renal cell carcinoma, pancreatic ductal adenocarcinoma, and non-small cell lung cancer, as well as various hematologic malignancies. By combining the targeting specificity of the Diakine platform with a potent cytotoxic agent, the drug aims to provide a more localized and effective treatment option while minimizing systemic toxicity.

Other names
Diakine Drug Conjugate
02

Targets

EGFR T790M (Epidermal growth factor receptor T790M mutant)

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