Drug intelligence / Profile preview

Dianeal

Development stage
Approved
Lead developer
Takeda
Modality
Small Molecules
Administration
Intraperitoneal
01

Overview

Dianeal is a sterile, non-pyrogenic peritoneal dialysis solution manufactured by Baxter, used primarily for the treatment of end-stage renal disease (ESRD) through continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD). It functions by utilizing dextrose as an osmotic agent to create a concentration gradient across the peritoneal membrane, facilitating the removal of excess fluid (ultrafiltration) and metabolic waste products, such as urea and creatinine, from the blood. The solution also contains essential electrolytes—including sodium, chloride, calcium, and magnesium—and lactate as a buffering agent to help maintain systemic acid-base and electrolyte balance. In clinical research, such as studies conducted at the Chinese PLA General Hospital, Dianeal often serves as the gold-standard comparator for evaluating the efficacy and safety of new peritoneal dialysate formulations.

Brand names
DianealDianeal PD-2Dianeal Low Calcium
Other names
Baxter Peritoneal DialysateBaxter Peritoneal Dialysate-Chinese PLA General Hospital-end stage renal diseasePeritoneal Dialysis Solution

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