Drug intelligence / Profile preview

Diapodil

Development stage
Unknown
Lead developer
Epitech
Modality
Small Molecules
Administration
Topical
01

Overview

Diapodil is a topical ALIAmide-based formulation developed by Epitech for the management of foot skin and nail disorders, specifically targeting complications associated with diabetic foot syndrome. The primary active ingredient is adelmidrol, a synthetic analogue of the endogenous lipid palmitoylethanolamide (PEA). Diapodil functions through the ALIA (Autacoid Local Inflammation Antagonism) mechanism, which involves the down-regulation of mast cell activation and degranulation. By modulating dermo-epidermal hyper-reactivity and reducing the release of pro-inflammatory mediators, the formulation helps maintain skin homeostasis, supports the repair of the skin barrier, and prevents the progression of inflammatory lesions in patients with peripheral neurovascular impairment.

Brand names
Diapodil
Other names
DIAPODIL

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