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DIBNEPAN
- Development stage
- Unknown
- Lead developer
- Biokindle Lifesciences
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
**DIBNEPAN** is an oral fixed-dose capsule developed for neuropathic pain, including diabetic neuropathic pain and diabetic peripheral neuropathy. It contains bio-optimized palmitoylethanolamide, diacerein, and biochanin A. The sponsor attributes its anti-inflammatory and analgesic activity principally to palmitoylethanolamide-mediated activation of peroxisome proliferator-activated receptor alpha, with associated suppression of mast-cell degranulation, oxidative stress, and inflammatory enzyme activity. ([biokindle.com](https://www.biokindle.com/products-biokindle/dibnepan/))
- Brand names
- DIBNEPAN
- Other names
- bio-optimized palmitoylethanolamide + diacerein + biochanin A
02
Targets
PPARA (Peroxisome proliferator-activated receptor alpha)FAAHTRPV1 (Transient receptor potential cation channel subfamily V member 1)NAAA (N-acylethanolamine-hydrolyzing acid amidase)NOS3 (eNOS)COXNOS2 (Nitric Oxide Synthase 2)
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