Drug intelligence / Profile preview

dicalcium phosphate

Development stage
Phase 4
Lead developer
Kuraray Medical
Modality
Small Molecules
Administration
Oral, Topical, Implant
01

Overview

Dicalcium phosphate is an inorganic calcium salt (CaHPO4) that serves multiple roles in medicine, dentistry, and nutrition. In the pharmaceutical industry, it is a widely used excipient, functioning as a brittle filler or diluent in direct compression tableting. In dentistry, it is utilized in formulations for enamel remineralization and the treatment of dentin hypersensitivity, where it acts as a source of calcium and phosphate ions to facilitate the formation of hydroxyapatite. Its hydrated form, brushite (DCPD), and anhydrous form, monetite, are employed as resorbable bone graft substitutes in orthopedic and alveolar bone regeneration procedures. Furthermore, it is a common dietary supplement used to address mineral deficiencies in both human and veterinary medicine.

Brand names
Teethmate Desensitizer
Other names
dibasic calcium phosphatecalcium hydrogen phosphatecalcium monohydrogen phosphateDCPDCPDbrushitemonetitedicalcium phosphate dihydratedicalcium phosphate anhydrous
02

Targets

CaSR (Extracellular calcium-sensing receptor)

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