Drug intelligence / Profile preview

diclofenac potassium + paracetamol + serratiopeptidase (Ultrachem Pharmaceuticals)

Development stage
Unknown
Lead developer
Ultrachem Pharmaceuticals
Modality
Recombinant Proteins and Enzymes, Small Molecules
Administration
Oral
01

Overview

Bigflam is a fixed-dose combination tablet containing diclofenac potassium (a nonsteroidal anti-inflammatory drug), paracetamol (an analgesic and antipyretic), and serratiopeptidase (a proteolytic enzyme). It is primarily used for the short-term relief of moderate to severe pain, inflammation, and swelling associated with musculoskeletal disorders, joint pain, arthritis (such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis), dental pain, and post-operative recovery. Diclofenac potassium and paracetamol work synergistically to inhibit prostaglandin synthesis, thereby reducing pain and fever, while serratiopeptidase breaks down abnormal proteins at the site of inflammation to reduce swelling and promote tissue healing.

Brand names
Awaydol SPBigflamCipzen D PlusDafric SPDaklofen-SPDardflamDecplist SPDeezire-SPDICLOmera-SPDiclogesic-SPDicloniv SPDicloroot SPDiclotal-SPDicret SPEbilityEmanzen DPEnzoflamEsgipyrin SPFlozen-PlusGeyfen-SpKritdec SPLaadic-SPLyser DPNeopepPainwell-SPSeradic-PSeridase DPSeropen DPVelflam-SPVoltamax SPWoxterZeldinac-SPZinase-DP
Other names
diclofenac + paracetamol + serratiopeptidasediclofenac potassium + paracetamol + serratiopeptidasediclofenac potassium, paracetamol and serratiopeptidasediclofenac, paracetamol and serratiopeptidaseparacetamol + diclofenac potassium + serratiopeptidaseparacetamol, diclofenac potassium and serratiopeptidase
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)

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