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Diclosante is a branded generic formulation of diclofenac sodium, a nonsteroidal anti-inflammatory drug (NSAID) developed and marketed by Pharma Shimi. It is available as a rectal suppository in 50 mg and 100 mg strengths. Diclosante is used for the management of acute and chronic pain, inflammation, and musculoskeletal disorders. It exerts its therapeutic effects by inhibiting cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, thereby reducing the synthesis of pro-inflammatory prostaglandins.
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