Drug intelligence / Profile preview

Diclotrex II

Development stage
Unknown
Lead developer
Puretek
Modality
Small Molecules
Administration
Topical
01

Overview

**Diclotrex II** is a topical co-packaged analgesic kit marketed by PureTek. It contains diclofenac sodium topical solution 1.5% w/w plus a camphor 4% and menthol 10% topical gel product. Diclofenac is a nonsteroidal anti-inflammatory drug that inhibits cyclooxygenase enzymes and reduces prostaglandin-mediated pain and inflammation; camphor and menthol provide topical counterirritant analgesia. The diclofenac component is labeled for treatment of the signs and symptoms of osteoarthritis of the knee. The DailyMed listing identifies the product as an unapproved drug other and states that its labeling has not been approved by FDA. ([drugs.com](https://www.drugs.com/pro/diclotrex.html))

Brand names
DiclotrexDiclotrex II
Other names
diclofenac sodium + camphor + menthol
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)

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