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Dictyophleba setosa stem bark extract

Development stage: Preclinical
Lead developer: Muğla Sıtkı Koçman University
Modality: Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration: Oral

Overview

Dictyophleba setosa stem bark extract is a botanical extract derived from the stem bark of *Dictyophleba setosa*, a medicinal liana native to Central Africa [6527]. Traditionally used as a vermifuge in children, the extract has been investigated for its potential in preventing and managing gastric and peptic ulcers [6527]. It exhibits potent antioxidant and antiradical scavenging activities, as well as strong inhibitory activity against the urease enzyme produced by *Helicobacter pylori*, which is a key causative factor in peptic ulcer disease [6527].

Other names: DSS

Targets

Urease

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