Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
diethylammonium tetrathiomolybdate
- Development stage
- Preclinical
- Lead developer
- King's College London
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
Diethylammonium tetrathiomolybdate (DEATTM) is a slow-release hydrogen sulfide (H2S) donor under preclinical investigation for the treatment of ischemia-reperfusion injury (IRI), particularly in the context of hemorrhage-reperfusion. By releasing sulfide, DEATTM reversibly inhibits the mitochondrial electron transport chain, specifically targeting cytochrome c oxidase (Complex IV), which reduces metabolic activity and limits the excessive generation of reactive oxygen species (ROS) during reperfusion. Additionally, DEATTM exhibits short-term diuretic and natriuretic effects, likely mediated through the inhibition of renal tubular Na+/K+-ATPase.
- Other names
- diethyl-ammonium tetrathiomolybdate
02
Targets
COX7C (Cytochrome c oxidase subunit 7C, mitochondrial)ATP1A (Sodium/potassium-transporting ATPase)
Beyond the preview
Go deeper on diethylammonium tetrathiomolybdate.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on diethylammonium tetrathiomolybdate.