Drug intelligence / Profile preview

difinsa53

Development stage
Unknown
Lead developer
ProTechSure Scientific
Modality
Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Hydrogel Systems → Drug Delivery Systems, Classical Binding Small Molecules → Small Molecules
Administration
Topical
01

Overview

Difinsa53 is a topical skin protectant lotion developed by Protechsure Scientific to prevent and treat radiation-induced dermatitis and other forms of skin damage caused by exposure to therapeutic or solar radiation. The product contains dimethicone (1%) as its primary active ingredient, acting as a silicone-based barrier to protect, moisturize, and soothe the skin. Additionally, it includes silibinin, a botanical compound with antioxidant properties that may help mitigate DNA damage in skin cells exposed to radiation. The cream is marketed over-the-counter for use in patients undergoing radiation therapy for cancer—particularly breast cancer—to reduce the severity or incidence of radiation dermatitis. Clinical studies have evaluated its efficacy compared to standard treatments such as Aquaphor.

Brand names
Difinsa53Difinsa-53Difinsa 53

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