DIFIXN

DIFIXN is an oral **small molecule** veterinary anti-diarrheal product developed by Goldman Pharmaceutical Group for the temporary relief of diarrhea in dogs weighing 10 to 60 lbs. It contains **loperamide hydrochloride 2 mg per tablet** and is supplied as a green, oval-shaped tablet marketed as an over-the-counter animal drug. Loperamide acts primarily as a **peripherally acting opioid receptor agonist** in the gastrointestinal tract, slowing intestinal motility and thereby reducing diarrhea. The product labeling notes breed-specific safety warnings, including avoidance in collies, shelties, Australian shepherds, German shepherds, Old English sheepdogs, and long-haired whippets, and it has been described in DailyMed as a marketed animal drug whose labeling has not been approved by FDA and which has not been found by FDA to be safe and effective.

Brand names

DIFIXN

Other names

loperamide hydrochlorideloperamide HCl