Drug intelligence / Profile preview

diflucortolone valerate fatty ointment

Development stage
Unknown
Lead developer
Bayer
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Topical
01

Overview

**Diflucortolone valerate fatty ointment** is a very potent topical corticosteroid formulation indicated for the short-term treatment of severe inflammatory skin conditions such as eczema, psoriasis, and dermatitis that are unresponsive to less potent corticosteroids. It works by suppressing inflammation and allergic reactions locally in the skin, leading to a reduction in redness, swelling, itching, and discomfort. Diflucortolone valerate is a fluorinated corticosteroid, and topical application suppresses capillary dilatation, intercellular edema, and tissue infiltration, causing regression of inflamed skin and alleviation of subjective complaints such as itching and burning. Typically used when less potent steroids are ineffective[1][3][4][9].

Brand names
Nerisone fatty ointmentNerisone Forte fatty ointment
Other names
diflucortolone valerate ointmentNerisone ointmentNerisone Forte ointment
02

Targets

GR (Glucocorticoid receptor)

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