Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
digoxin immune fab
- Development stage
- Approved
- Lead developer
- Bio-Technology General
- Modality
- Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
- Administration
- Intravenous
01
Overview
Digoxin immune fab is an antibody fragment derived from sheep immunized with a digoxin derivative. It consists of antigen-binding fragments (Fab) that specifically bind to and neutralize free digoxin or digitoxin molecules in the bloodstream. By binding these cardiac glycosides, it prevents them from interacting with their physiological target—the sodium-potassium ATPase pump—thereby reversing their toxic effects on the heart. The resulting Fab-digoxin complexes are then cleared by the kidneys and reticuloendothelial system. Digoxin immune fab is used as an antidote for life-threatening overdose or toxicity of digoxin or digitoxin and is administered intravenously in hospital settings[1][2][3][4][5][6][8].
- Brand names
- DigibindDigiFab
- Other names
- digoxin immune fabdigoxin immune fab (ovine)DIF
02
Targets
ATP1A2 (Na+/K+-ATPase alpha-2)
Beyond the preview
Go deeper on digoxin immune fab.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on digoxin immune fab.