Drug intelligence / Profile preview

dihexyverine

Development stage
Unknown
Lead developer
Mead Johnson Nutrition
Modality
Small Molecules
Administration
Oral
01

Overview

Dihexyverine is a small molecule antispasmodic and smooth muscle relaxant belonging to the piperidine class. It acts primarily as an antimuscarinic (muscarinic acetylcholine receptor antagonist), leading to relaxation of smooth muscle in the gastrointestinal and genitourinary tracts. Its main clinical use is for the treatment of functional gastrointestinal disorders such as irritable bowel syndrome, spastic colon, and related conditions. Dihexyverine exerts its effects by inhibiting muscarinic acetylcholine receptors, thereby reducing parasympathetic nervous system activity and alleviating spasms[1][4][5][6].

Brand names
metaspasspasmolevelspasmodexseclinolimplexneospasminadiverine
Other names
dihexyverine hydrochloride
02

Targets

mAChR (Muscarinic acetylcholine receptors)

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