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Dihuang Yizhi Formula
- Development stage
- Unknown
- Lead developer
- Shanghai University of Traditional Chinese Medicine
- Administration
- Oral
01
Overview
Dihuang Yizhi Formula is a Traditional Chinese Medicine (TCM) herbal composition developed by Longhua Hospital, Shanghai University of Traditional Chinese Medicine, for the treatment of cognitive impairment. The formula typically includes *Rehmannia glutinosa*, *Cornus officinalis*, *Panax ginseng*, *Acorus tatarinowii*, *Polygala tenuifolia*, and *Poria cocos*. It is investigated for its potential to treat subjective cognitive decline, mild cognitive impairment, and Alzheimer's disease. Mechanistically, it is thought to provide neuroprotection by modulating the cholinergic system, reducing neuroinflammation, and inhibiting the accumulation of amyloid-beta plaques.
- Other names
- DHYZ formulaDihuang Yizhi decoctionDihuang Yizhi granule
02
Targets
AcetylcholinesteraseAβ (Amyloid-beta peptides and aggregates)
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