Drug intelligence / Profile preview

dihydrocodeine thiocyanate

Development stage
Unknown
Lead developer
SALARAS
Modality
Small Molecules
Administration
Oral
01

Overview

Dihydrocodeine thiocyanate is a semi-synthetic opioid analgesic and antitussive, primarily utilized for the management of moderate to severe pain and the suppression of non-productive cough. It acts as an agonist at the mu-opioid receptors ($\mu$-receptors) within the central nervous system, mimicking the effects of endogenous endorphins to produce analgesia, sedation, and cough suppression. As a derivative of codeine, dihydrocodeine exhibits approximately twice the analgesic potency. The thiocyanate salt form is commonly used in pharmaceutical formulations, particularly in Europe, and is available in various dosage forms such as oral drops and solutions. SALARAS is a notable manufacturer of this active pharmaceutical ingredient.

Brand names
Paracodina
Other names
Diidrocodeina TiocianatoDihydrocodeine rhodanide
02

Targets

DOR (Opioid Receptor Delta 1)KOR (Kappa opioid receptor)MOR (Mu opioid receptor)

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