Drug intelligence / Profile preview

dihydrodesoxycodeine-D

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Subcutaneous, Intramuscular, Rectal
01

Overview

Dihydrodesoxycodeine-D is a semi-synthetic opioid compound, historically described as a chemical intermediate or derivative related to codeine. It is produced through the catalytic reduction of α-chlorocodide, itself derived from codeine, and serves as a precursor in the synthesis of other opioids, such as dihydrodesoxymorphine-D (desomorphine)[4][6]. Dihydrodesoxycodeine-D is not used clinically as an approved medication, but is relevant in the context of opioid chemistry and synthesis. Its mechanism of action would theoretically involve agonism at the mu-opioid receptor, as with other opioids, leading to analgesic and sedative effects; however, no direct clinical use or pharmacological data are reported for the compound itself.

Other names
desocodeine
02

Targets

DOR (Opioid Receptor Delta 1)KOR (Kappa opioid receptor)MOR (Mu opioid receptor)

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