dilazep

Dilazep is a small molecule vasodilator that acts primarily as an adenosine reuptake inhibitor. It exhibits antiplatelet, antianginal, and vasodilator properties. By inhibiting the cellular uptake of adenosine via equilibrative nucleoside transporter 1 (SLC29A1), it increases extracellular adenosine concentrations, leading to vasodilation and inhibition of platelet aggregation. Dilazep also improves blood flow in coronary and renal vessels, protects cardiac muscle, reduces proteinuria in renal dysfunction, and is used clinically for the treatment of ischemic heart disease (including angina), cerebral ischemia, and certain renal disorders[1][3][4][5][7]. Its mechanism includes reducing thromboxane B2 formation by impairing arachidonic acid release from platelet membranes[6].

Brand names

Comelian KowaDILAZEP HYDROCHLORIDE TABLETS 100mg "TOWA"

Other names

dilazepDilazepamDilazepumBiopropazepan Trimethoxybenzoate