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dimethicone + chlorhexidine gluconate + mupirocin
- Development stage
- Approved
- Lead developer
- NuCare Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Dimethicone + chlorhexidine gluconate + mupirocin is a topical perioperative combination kit product marketed as NuSurgePak Surgical Prep/CarePak that combines a skin protectant, an antiseptic, and a topical antibacterial. The mupirocin component is a **small-molecule antibiotic** that inhibits bacterial isoleucyl-tRNA synthetase, thereby blocking bacterial protein synthesis; it is used for topical treatment of impetigo caused by susceptible *Staphylococcus aureus* and *Streptococcus pyogenes*. The chlorhexidine gluconate component is a broad-spectrum topical antiseptic used for surgical hand scrub and preoperative skin preparation, while dimethicone functions as a skin protectant barrier. The product has been distributed or manufactured in marketed kit formulations by companies including Nucare Pharmaceuticals, Xttrium Laboratories, Glenmark, and PureTek for surgical prep/care use and topical antibacterial skin care.
- Brand names
- NuSurgePak Surgical Prep/CarePak
- Other names
- chlorhexidine gluconate + dimethicone + mupirocinmupirocin + chlorhexidine gluconate + dimethicone
02
Targets
IleRS (Isoleucyl-tRNA synthetase)
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