Drug intelligence / Profile preview

dimethicone + fluocinonide

Development stage
Unknown
Lead developer
Valeant Pharmaceuticals
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Topical
01

Overview

This combination is a topical preparation. **Fluocinonide** is a strong topical corticosteroid used to treat skin conditions such as eczema, psoriasis, and dermatitis by reducing inflammation and symptoms like redness, itching, and swelling. **Dimethicone** is an emollient used to moisturize and protect the skin. Together, they help relieve skin irritation while maintaining skin hydration.

Brand names
Fluopar
02

Targets

ESRRA (Estrogen-related receptor alpha)ESRRB (Estrogen-related receptor beta)ESRRG (Estrogen-related receptor gamma)GR (Glucocorticoid receptor)SMO (Smoothened)

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