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DIOSynVax Universal Influenza vaccine

Development stage
Preclinical
Lead developer
DIOSynVax
Modality
Prophylactic Vaccines → Vaccines & Immunotherapeutics, mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Administration
Intranasal, Intramuscular (potentially; Primary Focus On Mucosal/intranasal Delivery)
01

Overview

The DIOSynVax Universal Influenza vaccine is an investigational next-generation universal influenza vaccine developed by DioSynVax, a company based at the University of Cambridge. The vaccine is designed to provide broad protection against multiple influenza virus strains, including all major clades of the H5 avian flu subtype. It utilizes advanced artificial intelligence-driven antigen design and is being developed as an mRNA-based platform, with potential for mucosal (intranasal) delivery to enhance uptake and immune response. The technology aims for rapid scalability and global distribution, targeting both seasonal and pandemic influenza threats[2][4][10]. As of 2025, it remains in preclinical development.

Brand names
DIOSynVax Universal Influenza vaccine
Other names
Universal Influenza Vaccine (DIOSynVax)
02

Targets

HA (Hemagglutinin)

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