diphenhydramine + guaifenesin + levomenthol

Antuss Plus is an oral combination medication developed by Gaco Pharmaceuticals, designed for the symptomatic relief of coughs and congestion associated with the common cold and respiratory infections. The formulation contains three active ingredients: diphenhydramine hydrochloride, guaifenesin, and levomenthol. Diphenhydramine is a first-generation antihistamine that acts as an H1-receptor antagonist, providing antitussive effects by reducing the cough reflex and alleviating allergic symptoms. Guaifenesin is an expectorant that works by increasing the volume and reducing the viscosity of respiratory tract secretions, thereby facilitating the clearance of mucus from the airways. Levomenthol provides a cooling sensation and mild local anesthetic effect on the throat and nasal passages by acting as a TRPM8 agonist. Together, these components address both productive and non-productive coughs while soothing irritated respiratory tissues.

Brand names

Antuss Plus

Other names

Antuss Plus-Gaco Pharmaceuticals-oralDiphenhydramine / Guaifenesin / Levomenthol