Drug intelligence / Profile preview

diphtheria-tetanus-pertussis vaccine

Development stage
Approved
Lead developer
Sanofi
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

A combination vaccine indicated for the prevention of diphtheria, tetanus, and pertussis (whooping cough). It consists of diphtheria toxoid, tetanus toxoid, and acellular components of Bordetella pertussis (such as inactivated pertussis toxin, filamentous hemagglutinin, pertactin, and fimbriae), adsorbed onto an aluminum-based adjuvant. It is administered intramuscularly and stimulates active immunity by inducing antibody production against the toxins and antigens of the three bacteria, thereby preventing the associated diseases[1][3][7]. The DTaP formulation is primarily for children under 7 years; Tdap is for older children, adolescents, and adults[2][6][7].

Brand names
DaptacelInfanrixAdacelBoostrix
Other names
DTaP vaccineTdap vaccinediphtheria, tetanus, and pertussis vaccineacellular pertussis vaccine
02

Targets

TT (Tetanus toxoid)

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