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diphtheria toxoid + tetanus toxoid + acellular pertussis vaccine + hepatitis B vaccine + haemophilus influenzae type b conjugate vaccine
- Development stage
- Phase 3
- Lead developer
- Merck
- Modality
- Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
diphtheria toxoid + tetanus toxoid + acellular pertussis vaccine + hepatitis B vaccine + haemophilus influenzae type b conjugate vaccine is a pharmaceutical combination vaccine administered to infants and young children to provide active immunization against five serious diseases: diphtheria, tetanus, pertussis (whooping cough), hepatitis B, and invasive disease caused by Haemophilus influenzae type b. This pentavalent vaccine stimulates the immune system to generate protective antibodies against each targeted pathogen, thus preventing morbidity and mortality associated with these diseases. Its primary indication is routine childhood immunization beginning as early as 6 weeks of age. The vaccine combines toxoid and conjugate technologies, leveraging safe, inactivated bacterial components (diphtheria and tetanus toxoids, acellular pertussis antigens) and a conjugated polysaccharide for Hib to elicit robust immune responses[1][2][3][4].
- Brand names
- Vaxelis
- Other names
- DTaP-HepB-HibDTwP-HepB-Hibpentavalent vaccine5-in-1 vaccine
02
Targets
HBsAg (Hepatitis B surface antigen)Diphtheria toxin
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