Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
diprophylline
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Diprophylline (also known as dyphylline) is a xanthine derivative and theophylline analog with bronchodilator and vasodilator properties. It is primarily used in the treatment of respiratory disorders such as asthma, chronic bronchitis, emphysema, and cardiac dyspnea. Diprophylline acts mainly by antagonizing adenosine receptors and inhibiting phosphodiesterase enzymes (notably type III or IV), leading to increased cyclic AMP levels in smooth muscle cells. This results in relaxation of bronchial smooth muscle and dilation of airways. Additional effects include mild diuretic action and stimulation of the central nervous system's respiratory centers[2][5][6]. The drug is administered orally.
- Brand names
- DilorLufyllinDylixDilor-200Dilor200Dilor 200Dilor-400Dilor400Dilor 400Lufyllin-400Lufyllin400Lufyllin 400
- Other names
- 7-(2,3-Dihydroxy-propyl)theophylline
02
Targets
ADORA1 (Adenosine receptor A1 subtype)ADORA2A (Adenosine A₂A Receptor)PDE3PDE4 (Phosphodiesterase 4A1)
Beyond the preview
Go deeper on diprophylline.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on diprophylline.