Drug intelligence / Profile preview

disodium cromoglycate + reproterol

Development stage
Unknown
Lead developer
Sanofi
Modality
Small Molecules
Administration
Inhalation
01

Overview

Disodium cromoglycate (also known as cromoglicic acid or sodium cromoglycate) combined with reproterol is a fixed-dose inhaled therapy used primarily for the treatment and prevention of asthma, including allergic, non-allergic, and exercise-induced asthma. Disodium cromoglycate is a mast cell stabilizer that inhibits the release of inflammatory mediators from sensitized mast cells, providing bronchoprotective and anti-inflammatory effects. Reproterol is a short-acting β2-adrenoreceptor agonist that acts as a bronchodilator by stimulating β2 receptors in airway smooth muscle, leading to relaxation and relief of bronchospasm. The combination leverages both disease-modifying (cromoglicate) and symptomatic (reproterol) actions for improved asthma control[1][2][3][4].

Other names
cromoglicic acid + reproterolsodium cromoglycate + reproterolDSCG + reproterol
02

Targets

ADRB2 (β2)

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