Drug intelligence / Profile preview

dl-copper-cysteine

Development stage
Preclinical
Lead developer
Zanjan University of Medical Sciences
Modality
Nanoparticles → Drug Delivery Systems
Administration
Intratumoral
01

Overview

**dl-copper-cysteine** is an experimental racemic copper(II)-cysteine coordination nanoparticle system composed of Cu2+ and DL-cysteine ligands. In a preclinical 4T1 murine breast-cancer model, intratumoral administration combined with near-infrared irradiation was evaluated as a dual photothermal therapy and chemodynamic therapy approach. The nanoparticles generate heat under near-infrared exposure and promote reactive oxygen species formation through copper-mediated redox catalysis, producing tumor-cell death and reducing metastatic behavior in the reported model. ([pubs.rsc.org](https://pubs.rsc.org/ra/article/16/3/2167/909033/A-novel-copper-based-nanosystem-for-augmented))

Other names
dl-Cu-Cys NPsdl-Cu-Cys nanoparticlesdl-Cu-Cys-NPsdl-copper-cysteine nanoparticles

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