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DNA Nat-B env is a DNA vaccine component containing an HIV-1 envelope insert. It is designed to be part of a prime-boost HIV vaccine regimen, where it serves as the DNA prime vaccine. The vaccine aims to evaluate its safety, tolerability, and ability to elicit an immune response against HIV-1 in healthy, HIV-uninfected adults. It has been studied in clinical trials in combination with other boost vaccines like NYVAC Nat-B env or MVA-CMDR.
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