docusate + benzocaine

Docusate + benzocaine is a combination pharmacological agent used for the treatment of chronic constipation and bowel management, particularly in patients with spinal cord injuries or neurological disorders. Docusate sodium functions as an anionic surfactant and stool softener; it reduces the surface tension of the fecal mass, allowing water and lipids to penetrate and soften the stool, thereby facilitating easier evacuation. Benzocaine is a local anesthetic of the ester type that acts by inhibiting voltage-gated sodium channels on the neuronal membrane, providing a rapid numbing effect to the rectal mucosa. This combination not only eases the passage of stool but also minimizes the discomfort and pain associated with defecation. Beijing Beiliyuan Pharmaceutical Technology Co., Ltd. is a known developer of this combination, typically formulated as a rectal solution or mini-enema for rapid onset of action.

Brand names

Enemeez PlusDocu-Sol PlusTherevac-Plus

Other names

docusate sodium and benzocainebenzocaine and docusate sodium