Drug intelligence / Profile preview

docusate calcium

Development stage
Unknown
Lead developer
Sanofi
Modality
Small Molecules
Administration
Oral
01

Overview

Docusate calcium is an anionic surfactant that serves as a stool softener for the management of constipation. Its primary mechanism involves lowering the surface tension of the fecal mass, which promotes the incorporation of water and lipids into the stool, thereby softening it and facilitating easier evacuation without directly stimulating peristalsis. It is frequently indicated for patients who need to avoid straining during defecation, such as those recovering from abdominal surgery or a myocardial infarction. While effective for softening stool, it is generally considered a mild laxative and is often used for maintenance or in combination with stimulant laxatives for more comprehensive bowel management.

Brand names
SurfakKao-TinDocusoftCalubeDC Softgels
Other names
Dioctyl calcium sulfosuccinateCalcium bis(bis(2-ethylhexyl) sulfosuccinate)Docusate Ca

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