dodonaea viscosa hydroethanolic extract

Dodonaea viscosa hydroethanolic extract is a plant-based preparation obtained by macerating the leaves (and sometimes other aerial parts) of *Dodonaea viscosa* in a water-ethanol solution, typically around 70% ethanol[3][4]. This extract contains a range of bioactive phytochemicals, including flavonoids (such as isorhamnetin, quercetin, kaempferol, and apigenin), polyphenols, saponins, triterpenes, coumarins, tannins, and phenols[3][2][4]. The hydroethanolic extract demonstrates multiple pharmacological activities, notably **cytotoxicity and antiproliferative effects** against various cancer cell lines (including colorectal, breast, lung, and ovarian cancer), **anti-inflammatory**, **antimicrobial**, and **antioxidant** actions[3][4][5][1]. Mechanistically, antitumor effects are associated with induction of mitochondrial-dependent apoptosis (upregulation of caspase 3, p53), cell cycle arrest, and loss of mitochondrial membrane potential in tumor cells[3][4]. It is also traditionally used for disorders such as rheumatism, skin infections, gastrointestinal ailments, and wound healing[1][2][6]. It is not a registered pharmaceutical; uses are predominantly medicinal, ethnobotanical, or experimental.

Other names

dodonaea viscosa extractsticky hop bush hydroethanolic extract