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dog hair allergen immunotherapy preparation
- Development stage
- Preclinical
- Lead developer
- ALK Abelló
- Modality
- Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
- Administration
- Subcutaneous
01
Overview
Dog hair allergen immunotherapy preparation is an allergen-specific immunotherapy (AIT) in development by ALK-Scherax (a subsidiary of ALK-Abelló) for the treatment of dog allergy and associated allergic rhinitis. The preparation consists of dog hair and dander allergen extracts (including major allergens such as Can f 1). Its mechanism of action involves the gradual administration of these allergen extracts to induce immunological tolerance, shifting the immune response away from an IgE-mediated allergic reaction and reducing symptoms upon natural exposure to dogs.
- Other names
- Dog allergen AIT preparation
02
Targets
Can f 1IgE (Immunoglobulin E)
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