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Drug intelligence / Profile preview
Dolomec
- Development stage
- Unknown
- Lead developer
- McW Healthcare
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
**Dolomec** is a marketed oral fixed-dose analgesic and antipyretic combination from McW Healthcare containing ibuprofen 400 mg, methionine 50 mg, and paracetamol 500 mg per tablet. It is used for pain, inflammation, and fever, including musculoskeletal pain and inflammatory arthritic conditions. Ibuprofen provides nonsteroidal anti-inflammatory activity through inhibition of prostaglandin synthesis, while paracetamol contributes analgesic and antipyretic effects; methionine is an amino-acid component of the formulation. ([1mg.com](https://www.1mg.com/drugs/dolomec-tablet-278679))
- Brand names
- Dolomec
- Other names
- ibuprofen + methionine + paracetamol
02
Targets
Hb (Hemoglobin)PTGES3PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)NET (Norepinephrine Transporter)SERT (Sodium-dependent serotonin transporter)TRPV1 (Transient receptor potential cation channel subfamily V member 1)
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