donepezil + rosiglitazone

This is a combination drug consisting of donepezil and rosiglitazone. Donepezil is an acetylcholinesterase inhibitor primarily used to treat cognitive symptoms in Alzheimer's disease by increasing acetylcholine levels in the brain[2]. Rosiglitazone is a thiazolidinedione class antidiabetic agent that acts as a selective agonist of peroxisome proliferator-activated receptor gamma (PPARγ), improving insulin sensitivity and glycemic control, and has been investigated for potential neuroprotective effects, including possible benefits in cognitive function[5][1][3]. The combination has been proposed for the improvement of cognitive function, particularly in Alzheimer's disease or related dementias[1][3].