Drug intelligence / Profile preview

donzakimig

Development stage
Phase 2
Lead developer
UCB
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravenous, Subcutaneous
01

Overview

Donzakimig is a bispecific monoclonal antibody developed by UCB Biopharma that targets both interleukin-13 (IL-13) and interleukin-22 (IL-22). It is being investigated primarily for the treatment of atopic dermatitis. The drug acts as an immunomodulator by inhibiting the activity of IL-13 and IL-22, cytokines involved in inflammatory pathways associated with skin disorders. Donzakimig is currently in phase 1/2 clinical trials for atopic dermatitis[2][4][8].

Other names
donzakimigUCB1381UCB-1381UCB 1381
02

Targets

IL-13 (Interleukin-13)IL22 (Interleukin 22)

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