dopamine + dextrose

Dopamine + dextrose is a sterile premixed intravenous solution containing dopamine hydrochloride (a catecholamine inotropic/vasopressor agent) dissolved in 5% dextrose as a stabilizing vehicle and calorie source. Dopamine acts primarily as a sympathomimetic amine with dose-dependent agonist activity on dopamine (D1, D2), beta-1, and at higher doses, alpha-1 adrenergic receptors. It increases cardiac contractility and output (inotropy), improves renal and mesenteric blood flow, and at higher doses causes vasoconstriction to treat hypotension. The addition of dextrose provides calories and prevents hypoglycemia. The main clinical uses are for the correction of hemodynamic imbalances seen in shock (due to myocardial infarction, trauma, sepsis, open-heart surgery, renal failure), low cardiac output, and as adjunct in congestive heart failure or post-operative states requiring inotropic support[1][2][4][8][10][11].

Brand names

Dopamine Hydrochloride and 5% Dextrose InjectionDopamine HCl in 5% Dextrose

Other names

dopamine hydrochloride and 5% dextrosedopamine/dextrose premix