Drug intelligence / Profile preview

doravirine + dolutegravir + lamivudine

Development stage
Unknown
Lead developer
Merck
Modality
Small Molecules
Administration
Oral
01

Overview

This is a combination of three antiretroviral medications: doravirine (a non-nucleoside reverse transcriptase inhibitor, NNRTI), dolutegravir (an integrase strand transfer inhibitor, INSTI), and lamivudine (a nucleoside reverse transcriptase inhibitor, NRTI). Based on the provided information, this specific three-drug combination does not appear to be available as a single approved fixed-dose combination product, though its individual components and other combinations involving these drugs (like doravirine/lamivudine/tenofovir, dolutegravir/lamivudine, or doravirine/dolutegravir dual therapy) are used for HIV treatment.

02

Targets

Human immunodeficiency virus type 1 reverse transcriptaseIntegrase allosteric pocket (HIV)

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