Drug intelligence / Profile preview

Double anti-B867-ADC

Development stage
Preclinical
Lead developer
Nanolattix
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

Double anti-B867-ADC is a preclinical bispecific antibody-drug conjugate (ADC) being developed by Nanolattix for the treatment of malignant solid tumors. As a bispecific ADC, the molecule is engineered to recognize two different antigens or two distinct epitopes, which may enhance tumor selectivity and promote efficient internalization of the cytotoxic payload. This approach aims to improve the therapeutic index by concentrating the drug's effect within the tumor microenvironment while sparing healthy tissue. The specific targets associated with the B867 designation have not been publicly disclosed. The candidate is currently undergoing preclinical evaluation to support future clinical development.

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