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doxorubicin + bleomycin + vinblastine + dacarbazine + methylprednisolone

Development stage: Preclinical
Lead developer: Farmitalia
Modality: Small Molecules
Administration: Intravenous, Oral

Overview

This is a chemotherapy combination containing doxorubicin, bleomycin, vinblastine, dacarbazine, and methylprednisolone. It appears to be a modified version of the standard ABVD regimen (which contains only doxorubicin, bleomycin, vinblastine, and dacarbazine) with the addition of methylprednisolone, a corticosteroid. The standard ABVD regimen is commonly used for treating Hodgkin lymphoma. These chemotherapy drugs destroy quickly dividing cells, such as cancer cells.

Targets

TOP2A (DNA topoisomerase II)TUBB (Tubulin (alpha and beta subunits))GR (Glucocorticoid receptor)DNA

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