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doxorubicin-loaded DC Bead

Development stage: Unknown
Lead developer: Biocompatibles International
Modality: Small Molecules
Administration: Intra-arterial

Overview

Doxorubicin-loaded DC Bead is a drug-device combination used for transarterial chemoembolization of liver tumors, particularly hepatocellular carcinoma. It consists of DC Bead embolic microspheres loaded ex vivo with the anthracycline doxorubicin and administered selectively through the hepatic artery. The microspheres occlude tumor-feeding vessels while locally and sustainably eluting doxorubicin, combining ischemic embolization with locoregional cytotoxic chemotherapy. DC Bead is marketed by Boston Scientific and is compatible with doxorubicin for local treatment of hepatocellular carcinoma. ([bostonscientific.com](https://www.bostonscientific.com/en-EU/products/embolics/dc-bead.html))

Other names: DC Bead loaded with doxorubicinDEBDOXdoxorubicin-eluting DC Bead

Targets

DNATOP2A (DNA topoisomerase II)

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