Drug intelligence / Profile preview

DpC

Development stage
Phase 1
Modality
Small Molecules
Administration
Oral
01

Overview

DpC is an orally administered investigational drug currently in Phase 1 clinical development for the treatment of advanced solid tumors. The ongoing study aims to establish the maximum tolerated dose, evaluate its safety and tolerability, and explore its preliminary anti-tumor activity.

Other names
di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone hydrochloridedi2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone hydrochloridedi 2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone hydrochlorideDPC1-cyclohexyl-3-(dipyridin-2-ylmethylideneamino)-1-methylthiourea hydrochloride
02

Targets

JNK (Mitogen-activated protein kinase kinase kinase family)NF-κBTNFA (Tumor necrosis factor alpha (soluble))

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